PT-141 10MG

PT-141 (bremelanotide) is a cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone, developed through melanocortin-receptor research. It originated from investigations into the MT-II scaffold, where researchers sought to separate the melanocortin system's pigmentation effects from its central signaling activities. PT-141 shows preferential engagement of MC4R and MC3R subtypes — receptors densely expressed in hypothalamic circuits governing behavioral and autonomic regulation — and it became the primary tool compound for studying melanocortin signaling in those pathways. In preclinical models, it has been investigated in behavioral paradigms, erectile-function models, and energy-homeostasis studies, giving it a distinctive footprint at the intersection of neuroendocrinology and behavioral pharmacology. Its cyclic structure, shared with MT-II, provides proteolytic stability relevant to in vivo experimental design. This 10MG presentation is the standard format for melanocortin research programs. The compound's MC4R-centered pharmacology also makes it relevant to energy-homeostasis research, where hypothalamic melanocortin circuits are a major focus. For laboratory research use only. Not for human or veterinary use.