5-Amino-1MQ 10MG

5-Amino-1MQ is a small-molecule compound developed for research into nicotinamide N-methyltransferase (NNMT), an enzyme that has drawn sustained attention in metabolic research. NNMT catalyzes the methylation of nicotinamide, a reaction positioned at the intersection of NAD+ salvage pathways and cellular energy regulation. In preclinical literature, elevated NNMT activity has been documented in adipose tissue models associated with metabolic dysfunction, making selective NNMT inhibition an active area of laboratory investigation. 5-Amino-1MQ is studied as a cell-permeable NNMT inhibitor that lets researchers probe how modulating this enzyme influences downstream metabolic signaling in cell culture and animal models. Unlike peptide-based research materials, it is a quinoline-derived small molecule with distinct physicochemical properties relevant to assay design and solubility testing. This 10MG presentation provides a standard research quantity suited to pilot studies, dose-ranging experiments, and mechanistic work in vitro. Cell-permeability is a practical advantage in assay design, allowing direct application in culture systems without specialized delivery vehicles. For laboratory research use only. Not for human or veterinary use.