kisspeptin10 10MG

Kisspeptin-10 is the minimal active fragment of kisspeptin, a 54-amino-acid neuropeptide whose discovery reshaped reproductive endocrinology. The turning point came when genetic studies linked loss-of-function mutations in the kisspeptin receptor (KISS1R) to hypogonadotropic hypogonadism — establishing kisspeptin signaling as the gatekeeper of GnRH release and, by extension, puberty and fertility. The 10-amino-acid C-terminal fragment retains receptor activity in a compact, synthetically tractable form, making it the standard tool for probing this axis in the laboratory. Research applications include GnRH-neuron activation studies, puberty-timing models, and investigations of kisspeptin's emerging roles outside reproduction, such as metabolic and behavioral paradigms. Because the fragment is short and well-characterized, it is also used in receptor-mapping and structure-activity studies of the KISS1R system. This 10MG presentation suits neuroendocrine research programs. Ongoing research continues to expand the compound's footprint into metabolic and behavioral paradigms, where kisspeptin signaling is increasingly recognized as an integrative node. For laboratory research use only. Not for human or veterinary use.